A Database of Full-length cDNA of Entamoeba
Entamoeba histolytica is a protozoan parasite which predominantly infects humans and other primates and leads to amebiasis, estimated to cause more than 70,000 deaths world wide every year. The pathological mechanism of its host infection ramains unclear. It also has many unusual genomic features, some of which are shared with other protozoan parasites. We have constructed full-length cDNA libraries of E. histolytica and a reptilian parasites E. invadens using the Oligo-capping method(see detail here).
Full-Entamoeba, a database of Entamoeba full-length cDNAs, provides a web-based interface to search specific gene entries of your interest. It also functions as an integrated warehouse of various types of related biological data which are rapidly increasng with development of high-throughput technology and bioinformatics methodology. Thus, people this database targets on are not only experimental biologists who are interested in specific genes, but also bioinformaticians who are eager to perform large-scale genomic and transcriptomic analyses.
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Acknowledgements
Full-Entamoeba project is partly supported by The Jikei University Research Fund.
Computer resource is provided by Super Computer System in Institute for Chemical Research, Kyoto University.